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Hematol Oncol ; 38(5): 648-653, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-710365

ABSTRACT

The coronavirus disease (COVID-19) pandemic has posed several challenges to the hematology community to re-organize the medical care of patients with hematologic malignancies. Whereas the oncology societies favored a more or less conservative approach which considered the possibility of delaying treatment administration on a case-by-case basis, the hematology community guidelines were less stringent and recommended adequate individualized regimens. As countries are de-escalating the lockdown and the medical community is unable to foresee the end of the current outbreak will and whether the pandemic would eventually come back as a seasonal infection, there is interest in screening of patients with hematology malignancies with COVID-19 instead of limiting access to curative treatments. The rapidly accumulating knowledge about COVID-19 allows a better understanding of the diagnostic tools that may be potentially used in screening. Herein, we briefly review the pathophysiology of COVID-19, the rationale of screening of patients with hematologic malignancies, tools for screening, and available guidelines.


Subject(s)
COVID-19/complications , COVID-19/diagnosis , Hematologic Neoplasms/complications , SARS-CoV-2 , Adrenal Cortex Hormones/administration & dosage , Adrenal Cortex Hormones/adverse effects , Adrenal Cortex Hormones/therapeutic use , Antineoplastic Agents, Immunological/administration & dosage , Antineoplastic Agents, Immunological/adverse effects , Antineoplastic Agents, Immunological/therapeutic use , COVID-19/etiology , COVID-19/virology , Clinical Decision-Making , Colony-Stimulating Factors/administration & dosage , Colony-Stimulating Factors/adverse effects , Colony-Stimulating Factors/therapeutic use , Disease Management , Disease Susceptibility/immunology , Hematologic Neoplasms/therapy , Humans , Immunocompromised Host , Mass Screening , Molecular Diagnostic Techniques , Molecular Targeted Therapy/adverse effects , Molecular Targeted Therapy/methods , Practice Guidelines as Topic
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